Effects of oxymatrine on experimental hepatic fibrosis and its mechanism in vivo

Table 1 Effects of oxymatrine on expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) and α-smooth muscle actin (α-SMA) in the livers of rats with hepatic fibrosis (Ratio of positive areas).

Groups	n	TIMP-1	a-SMA
CCl4 group	8	35.07±6.50	24.89±5.32
CCl4+OM group	8	27.01±5.88a	21.64±2.36
OM group	8	2.16±1.16	4.46±1.47
Control group	8	2.48±1.40	12.52±17.6

^aP<0.05 vs CCl₄ group.