Tetrandrine inhibits activation of rat hepatic stellate cells in vitro via transforming growth factor-β signaling

doi:10.3748/wjg.v11.i19.2922

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May 21, 2005 (publication date) through Apr 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 21, 2005; 11(19): 2922-2926
Published online May 21, 2005. doi: 10.3748/wjg.v11.i19.2922

Table 1 Densitometric analysis of PCR products of each group (mean±SD).

Group	A_S/A_G	A_T/A_G
Control	11.5±0.5	78.5±0.4
Tet-0.25	27.3±0.3^a	34.1±0.3^a
Tet-0.5	25.9±0.2^a^c	12.6±0.3^a^c
Tet-1.0	67.0±1.0^a^c^e	9.5±0.3^a^c^e
Tet-2.0	67.4±0.2^a^c^e	9.5±0.1^a^c^e

^aP<0.05 vs control group.

^cP<0.05 vs Tet-0.25 group.

^eP<0.05 vs Tet-0.25, Tet-0.5 groups. A_S/A_G: Ratio of the densities of Smad 7 to that of GAPDH (%). A_T/A_G: Ratio of the densities of TGF-β₁ to that of GAPDH (%).

Citation: Chen YW, Wu JX, Chen YW, Li DG, Lu HM. Tetrandrine inhibits activation of rat hepatic stellate cells in vitro via transforming growth factor-β signaling. World J Gastroenterol 2005; 11(19): 2922-2926
URL: https://www.wjgnet.com/1007-9327/full/v11/i19/2922.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i19.2922