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©The Author(s) 2004.
World J Gastroenterol. Mar 1, 2004; 10(5): 737-740
Published online Mar 1, 2004. doi: 10.3748/wjg.v10.i5.737
Published online Mar 1, 2004. doi: 10.3748/wjg.v10.i5.737
Table 1 Clinicopathologic findings in patients with early gas-tric carcinoma with and without lymph node metastasis
| Node-negative | Node-positive | P value | |
| n = 673, (%) | n = 75, (%) | ||
| Age (mean, yr) | 55.7 ± 10.7 | 57.9 ± 10.7 | NS |
| Gender | < 0.05 | ||
| Male | 453 (67.3) | 41 (54.7) | |
| Female | 220 (32.7) | 34 (45.3) | |
| Age (yr) | NS | ||
| ≤ 40 | 71 (10.5) | 5 (6.7) | |
| > 40 | 602 (89.5) | 70 (93.3) | |
| Tumor size (mean, cm) | 2.2 ± 1.45 | 3.1 ± 1.89 | < 0.01 |
| < 2 | 434 (64.5) | 10 (13.3) | < 0.01 |
| 2-3 | 141 (21.0) | 24 (32.0) | |
| > 3 | 98 (14.5) | 41 (54.7) | |
| Tumor location | NS | ||
| Upper | 28 (4.2) | 2 (2.7) | |
| Middle | 200 (29.7) | 18 (24.0) | |
| Lower | 445 (66.1) | 55 (73.3) | |
| Macroscopic appearance | NS | ||
| Protruded | 208 (30.9) | 21 (28.0) | |
| Depressed | 417 (62.0) | 50 (66.7) | |
| Mixed | 48 (7.1) | 4 (5.3) | |
| Stage | < 0.01 | ||
| Ia | 672 (99.9) | ||
| Ib | 65 (86.7) | ||
| II | 6 (8.0) | ||
| IV | 1 (0.1) | 4 (5.3) | |
| Histologic type | < 0.01 | ||
| Differentiated | 348 (51.7) | 24 (32.0) | |
| Undifferentiated | 325 (48.3) | 51 (68.0) | |
| Depth of invasion | < 0.01 | ||
| Mucosa | 363 (53.9) | 14 (18.7) | |
| Submucosa | 310 (46.1) | 61 (81.3) | |
| Operative type | NS | ||
| Total gastrectomy | 62 (9.2) | 8 (10.7) | |
| Proximal gastrectomy | 4 (0.6) | ||
| Distal gastrectomy | 583 (86.8) | 65 (86.7) | |
| Others | 24 (3.4) | 2 (2.7) | |
| Lymph node dissection | < 0.01 | ||
| D1 | 144 (21.4) | 8 (10.7) | |
| D2 | 484 (71.9) | 50 (66.7) | |
| ≥ D3 | 45 (6.7) | 17 (22.7) | |
| Curability | NS | ||
| Curative | 671 (99.7) | 73 (97.3) | |
| Non-curative | 2 (0.3) | 2 (2.7) |
Table 2 Lymph node metastasis according to DNA ploidy pattern (n = 238)
| DNA ploidy | Node-negative (%) | Node-positive (%) | P value |
| Aneuploid | 80 (38.5) | 17 (56.7) | < 0.05 |
| Diploid | 128 (61.5) | 13 (43.3) |
Table 3 Logistic regression analysis for variables associated with lymph node metastasis in early gastric carcinoma
| Variables | Risk ratio | 95%CI | P value |
| Age | 1.040 | 0.996-1.021 | 0.50 |
| Gender | 1.022 | 0884-1.121 | 0.183 |
| Tumor size | 1.342 | 1.134-1.642 | 0.003 |
| Gross appearance | 1.124 | 0.987-1.342 | 0.384 |
| Histologic type | 0.948 | 0.737-1.221 | 0.009 |
| Depth of invasion | 1.241 | 0.949-1.369 | < 0.001 |
| Tumor location | 0.963 | 0.822-1.522 | 0.09 |
| DNA ploidy | 0.876 | 0.744-1.675 | 0.06 |
- Citation: Kim DY, Joo JK, Ryu SY, Kim YJ, Kim SK. Factors related to lymph node metastasis and surgical strategy used to treat early gastric carcinoma. World J Gastroenterol 2004; 10(5): 737-740
- URL: https://www.wjgnet.com/1007-9327/full/v10/i5/737.htm
- DOI: https://dx.doi.org/10.3748/wjg.v10.i5.737