Viral Hepatitis
Copyright ©The Author(s) 2004.
World J Gastroenterol. Mar 1, 2004; 10(5): 664-667
Published online Mar 1, 2004. doi: 10.3748/wjg.v10.i5.664
Table 1 Inhibitory effect of IRNA on HCV IRES mediated gene translation
SampleActivity of luciferaseActivity of luciferaseInhibitory rate (%)
pcRz-IRNA µgprogrammed by cap-dependentprogrammed bypcDNA-lucpCMVNCRluc
mechanism (IU/U)HCV IRES (IU/U)
055.5 ± 3.1152.49 ± 2.31
260.1 ± 2.3127.0 ± 0.740050
458.3 ± 1.8914.7 ± 0.380072
652.4 ± 2.124.03 ± 0.120492