FR167653 attenuates murine immunological liver injury

Table 1 Effect of FR167653 on serum TNF-α , NO and IL-1 from peritoneal macrophages in ILI mice

Group	Dose (mg/kg)	TNF-α (pg/mL)	NO (µmol/L)	IL-1 (103/min)
Normal	-	Under detection limit	15.7 ± 4.3	6.4 ± 1.42
Model	-	523.1 ± 28.6d	117.8 ± 10.7d	21.5 ± 5.04d
FR167653	50	491.8 ± 20.5a	109.3 ± 10.5	17.4 ± 3.81
	100	404.9 ± 18.5b	95.4 ± 8.9b	14.7 ± 3.05b
	150	341.8 ± 19.1b	84.3 ± 8.7b	11.9 ± 2.85b

n = 8, mean ± SD,

^aP < 0.05,

^bP < 0.01 vs model group;

^dP < 0.01 vs normal group.