Intestinal colonization with Candida albicans and mucosal immunity

Table 1 Proliferation and differentiation of lymphocytes

Group	Number of BrdU-positive cells sIgA in PP				Number of IgA plasma cells in LP
	n	PP	LP	Positive rates
Colonization
3 d	5	75 ± 12	0.30 ± 0.46	7.7 ± 1.2	0.68 ± 0.37
7 d	5	58 ± 20	1.05 ± 1.00	7.7 ± 2.5	0.67 ± 0.54
14 d	5	37 ± 10	3.34 ± 2.35a	ND	1.63 ± 0.52a
Control	5	70 ± 15	0.78 ± 1.04	10.3 ± 1.8	0.35 ± 0.15

^aP < 0.05 vs control; PP: Peyer’s patch; LP: Lamina propria; IgA plasma cells were counted after immunohistochemical stain as 40 villi/per mice and 5 mice/per time-point.

Table 2 Specific IgA to Candida albicans in intestinal mucus membrane

Group	n	Positive rate	Content (U/mg)
Colonization
3 d	20	5/20	33 ± 8
7 d	18	3/18	36 ± 13
14 d	25	10/25	69 ± 25a
Control	19	6/19	18.6 ± 6.9

^aP < 0.05 vs control.