Overexpression of annexin 1 in pancreatic cancer and its clinical significance

Table 1 Annexin I expression in normal pancreas and cancer tissues

Group	n	Positive rate of annexin I expression (%)	P value
Normal pancreas	38	18.4 (7/38)	< 0.0001
Pancreatic cancer	42	71.4 (30/42)
Ductal adenocarcinoma	32	75 (24/32)
Mucinous adenocarcinoma	6	83.3 (5/6)
Acinar cell carcinoma	4	25 (1/4)
Islet cell carcinoma	7	57.1 (4/7)
Ampulla of Vater carcinoma	7	57.1 (4/7)

Table 2 Correlation of annexin I expression with clinicopathologic factors of pancreatic adenocarcinoma on tissue microarray

Clinicopathologic factors	n	Positive expression rate of annexin I (%)	P value
Histological differentiation			0.012
High and moderate	21	71.4 (15/21)
Poor	11	81.8 (9/11)
Lymph node metastasis			0.810
Yes	8	75 (6/8)
No	34	73.5 (25/3)
TNM stage			0.551
I	15	66.7 (10/15)
II	21	81 (17/21)
III	5	60 (3/5)