Nitric oxide participates in protective effect of acupuncture on gastric mucosal damages in rats

doi:10.3748/wjg.v2.iSuppl1.59

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Sep 15, 1996 (publication date) through May 7, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 15, 1996; 2(Suppl1): 59-59
Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.59

Nitric oxide participates in protective effect of acupuncture on gastric mucosal damages in rats

Guan-Sun Xu, Zeng-Jiu Wang, Shun-Li Zhu, Quan-Zhu Chen, Dao-Qin Zhang

Guan-Sun Xu, Zeng-Jiu Wang, Shun-Li Zhu, Quan-Zhu Chen, Dao-Qin Zhang, Institute of Acupuncture and Meridian Anhui College of TCM, Hefei 230038, Anhui Province, China

Author contributions: All authors contributed equally to the work.

Received: November 12, 1995
Revised: April 22, 1996
Accepted: May 13, 1996
Published online: September 15, 1996

Abstract

AIM: The mucosal lesion index, gastric mucosal blood flow (GMBF), gastric electric activity (GEA), activity of nitric oxide synthesis (NOS) in mucosa contents of nitric oxide (NO) in serum were studied and effect of electrical acupuncture (EA) on above indices. On a rat model of restraint cold stress-induced gastric mucosal damages was established. Meanwhile, the protective effect of GMBF and GEA, gastric mucosal level of NOS, serum level of NO and stress-induced gastric mucosal damages in rats were closely related.

RESULTS: EA could effectively protect the gastric mucosal damages and increase previous quota. The mechanism of protective effect of EA on gastric mucosa was discussed.

CONCLUSION: We speculate that EA agitates the synthesis and release of NO in intestinal nerve system, NO mediates the integrity of gastric mucosa, endogenous NO participates in protective effect of EA on gastric mucosal damages.

Key Words: Nitric oxide, Electricalacupuncture, Gastric electric activity

Citation: Xu GS, Wang ZJ, Zhu SL, Chen QZ, Zhang DQ. Nitric oxide participates in protective effect of acupuncture on gastric mucosal damages in rats. World J Gastroenterol 1996; 2(Suppl1): 59-59
URL: https://www.wjgnet.com/1007-9327/full/v2/iSuppl1/59.htm
DOI: https://dx.doi.org/10.3748/wjg.v2.iSuppl1.59

Footnotes

Original title: China National Journal of New Gastroenterology (1995-1997) renamed World Journal of Gastroenterology (1998-).

E- Editor: Liu WX