Abstracts Open Access
Copyright ©The Author(s) 1996. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 15, 1996; 2(Suppl1): 204-204
Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.204
Efficacy of cisapride for therapy of constipation in aged patients
Chang-Qing Zhang, Department of Gastroenterology, the First Hospital, Quanzhou, China
Author contributions: The author solely contributed to the work.
Received: December 11, 1995
Revised: February 21, 1996
Accepted: July 19, 1996
Published online: September 15, 1996

Abstract

AIM: To observe the effect of cisapride on constipation in aged patients.

METHODS: 48 patients with constipation in aged were randomly assigned to 2 groups: 28 patients (M 18, F 10, age 72 ± 6) were treated with cisapride 10 mg po tid and 20 patients (M 13, F 7, age 73 ± 5) received placebo 2 tablets po tid. Both groups were treated for 8 wk.

RESULTS: The total effective rate was 75% in cisapride group and 30% in the placebo group, P < 0.01. Cisapride had no marked side effects.

CONCLUSION: Cisapride is a safe and effective drug for treatment of constipation in aged patients.

Key Words: Constipation, Cisapride



Footnotes

Original title: China National Journal of New Gastroenterology (1995-1997) renamed World Journal of Gastroenterology (1998-).

E- Editor: Liu WX

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