Abstracts Open Access
Copyright ©The Author(s) 1996. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 15, 1996; 2(Suppl1): 101-101
Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.101
Effect of gastrointestinal peptides on gastric emptying of rats with experimental duodenal ulcer
Xue-Jun Zhong, Gui-Yun Wu, Lu-Hui Wang, PLA 456 Hospital, Jinan 250031, Shandong Province, China
Author contributions: All authors contributed equally to the work.
Received: September 11, 1995
Revised: January 31, 1996
Accepted: July 1, 1996
Published online: September 15, 1996

Abstract

AIM: To study the effect of gastrointestinal peptides on gastric emptying of rats with duodenal ulcer.

METHODS: Gastrointestinal peptides were made from gastrointestinal muscosa in newborn cows. Wistar rats were randomly divided into groups. With phenolsulfonaphthalin as a marker the rate of gastric emptying was counted. The ulcer index was measured.

RESULTS: The rate of gastric emptying in non-ulcer control group was 75.43 ± 7.82, and in ulcer control group 94.41 ± 9.34 (P < 0.01). Treatment group was 78.01 ± 9.26. Compared with ulcer control group, the rate of gastric emptying and ulcer index in treatment group were remarkably decreased (P < 0.01).

CONCLUSION: Gastrointestinal peptides can promote ulcer healing and delay gastric emptying.

Key Words: Gastric emptying



Footnotes

Original title: China National Journal of New Gastroenterology (1995-1997) renamed World Journal of Gastroenterology (1998-).

E- Editor: Liu WX

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