Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats

Figure 1 Effects of SF on the expressions of iNOS, COX-2 and NF-κB P65 in the colonic tissue of rats colitis induced by acetic acid (n = 8, ¯x ± s). ^bP < 0.01, vs control group; ^cP < 0.05, ^dP < 0.01, vs model group.

Figure 2 Expressions of iNOS (A), COX-2 (B) and NF-κB p65 (C) in the inflammatory areas of colonic tissue from rats with colitis induced by acetic acid enema, respectively. The strongly positive signal were found. SP stain × 400.

Figure 3 Expressions of iNOS (A), COX-2 (B) and NF-κB p65 (C) were significantly decreaed in the colonic tissue from rats with colitis induced by acetic acid enema after treasted with 800 mg•kg^-1 ASP, respectively. The weakly positive staining could be found. SP stain × 400.