Synthesis of an enzyme-dependent prodrug and evaluation of its potential for colon targeting

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Oct 15, 2002 (publication date) through Apr 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 15, 2002; 8(5): 913-917
Published online Oct 15, 2002. doi: 10.3748/wjg.v8.i5.913

Figure 1 Preparation of DSD.

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Figure 2 The dexamethasone contents-time curves in cecum after the oral administration dexamethasone suspensions (●-●) and DSD suspensions (■-■)

Figure 3 The dexamethasone contents-time curves in colon after the oral administration dexamethasone suspensions (●-●) and DSD suspensions (■-■)

Citation: Pang YN, Zhang Y, Zhang ZR. Synthesis of an enzyme-dependent prodrug and evaluation of its potential for colon targeting. World J Gastroenterol 2002; 8(5): 913-917
URL: https://www.wjgnet.com/1007-9327/full/v8/i5/913.htm
DOI: https://dx.doi.org/10.3748/wjg.v8.i5.913