Association of hTcf-4 gene expression and mutation with clinicopathological characteristics of hepatocellular carcinoma

Figure 1 Expression of hTcf-4 and β-actin mRNA in HCC (Ca), para-cancerous tissue (P) and normal liver (N). Semiquantitative RT-PCR analysis revealed that the expression level of hTcf-4 gene in HCC was much higher than that in para-cancerous tissues and normal livers. M: 100 bp DNA Ladder

Figure 2 SSCP analysis of hTcf-4 exon 15 in HCC (Ca) and para-cancerous liver (P). Lane 1, abnormal SSCP pattern detected in exon 15 of patient 1, compared with the pattern of exon 15 from the corresponding para-cancerous liver in lane 2. Lane 3, normal SSCP pattern of exon 15 from patient 2, compared with the pattern of exon 15 from the corresponding para-cancerous liver in lane 4.