Effects of tachyplesin on the morphology and ultrastructure of human gastric carcinoma cell line BGC-823

Figure 1 BGC-823 cells. × 300

Figure 2 BGC-823 cells treated with tachyplesin. × 300

Figure 3 There are abundant microvilli on spherical cell surface and many filopodia emerge at the edge of BGC-823 cells. × 6000

Figure 4 The microvilli on spherical cell surface disappear mainly in the cells after tachyplesin treatment. × 6000

Figure 5 The microvilli are plentiful on flat and spread cell surface and many filopodia appear at the edge of BGC-823 cells. × 4800

Figure 6 On the cells treated with tachyplsin the microvilli are rare, shrink and shortened on flat and spread cell surface and large lame llipodia emerge at cell edge. × 4200

Figure 7 The nucleo-cytoplasm ratio is large, the shape of nucleus (N) is irregular and only a few organelle in cytoplasm of BGC-823 cells (Nu nucleolus, M mitochordria, ER endoplasmic reticulum). × 9600

Figure 8 The shape and structure of mitochondria (M) is non-typical and endoplasmic reticulum (ER) decrease in BGC-823 cells. × 40500

Figure 9 The cellular volume enlarge, the nucleo-cytoplasm ratio decreases and the organelle increase in the cells treated with tachyplesin. × 10720

Figure 10 The shape and structure of mitochondria (M) are unanimity relatively and their cristae increase and arrange rather regularly in the cells treated with tachyplsin. × 21000

Figure 11 The structure of Golgi complex (G) appear typical and well-developed in the cells treated with tachyplsin. × 48000