Basaloid squamous carcinoma of esophagus: a clinicopathological, immunohistochemical and electron microscopic study of sixteen cases

Figure 1 The basaloid cells arranged in the form of anastomosing trabeculae and microcystic structures. H&E, × 200

Figure 2 The intertrabecular and microcystic spaces filled with eosinophilic hyaline material which were PAS positive. × 100

Figure 3 Focal squamous differentiation and keratinization and comedo necrosis were found in the basaloid lobules. H&E, × 100

Figure 4 Basaloid cell carcinoma with spindle cell component. H&E, × 200

Figure 5 Immunohistochemical studies (S-P method) show positivity in the basaloid components for cytokeratin (Pan). × 200

Figure 6 The basaloid components in case 15 are diffusely and strongly positive staining for (a) vimentin and (b) S-100 protein. × 200

Figure 7 Electron microscopic photograph of esophage al BSC demontrating replicated basal lamina in fingerprint-like pattern filled in the intertrabecular and intercellular spaces. × 20000

Figure 8 Electron microscopicphotograph of esophageal BSC demonstrating well-formed intercellular desmosomes. × 16000