Expression and significance of HBV genes and their antigens in human primary intrahepatic cholangiocarcinoma

Figure 1 Cancerous surrounding hepatic tissue, HBxAg-positive substance located in the cytoplasms. ABC × 400

Figure 2 Cancerous and surrounding hepatic tissues, detection rate and intensity of the HBxAg-positive cells in the surrounding hepatic tissues were both higher than that in the cancerous tissues. ABC × 200

Figure 3 Cancerous tissue, HBsAg-positive substance located mainly in the cytoplasms. ABC × 200

Figure 4 Cancerous tissus, pre-S1 antigens located mainly in the cytoplasms, some on cellular membranes. ABC × 400

Figure 5 Surrounding hepatic tissue, HBc-Ag positive located mainly in the nuclei, some in the cytoplasms and on cellular membranes. ABC × 400

Figure 6 Surrounding hepatic tissue, HBV-DNA gene located in the cytoplasms, some in the nuclei. ISH × 400

Figure 7 Surrounding hepatic tissue, pre-S gene located in the cytoplasms, some in the nuclei. ISH × 400

Figure 8 Surrounding hepatic tissue, S gene located mainly in the cytoplasms. ISH × 400

Figure 9 Cancerous tissue, C gene located mainly in the nuclei, some in the cytoplasms. ISH × 400