Evaluating the scope of human leukocyte antigen polymorphisms influencing hepatitis B virus-related liver cancer and cirrhosis through multi-clustering analysis

doi:10.3748/wjg.v31.i7.102632

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Feb 21, 2025 (publication date) through Jan 20, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2025; 31(7): 102632
Published online Feb 21, 2025. doi: 10.3748/wjg.v31.i7.102632

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Figure 1 Machine learning revealed the complex relationship between different genotypes and hepatitis B virus liver diseases. CD74: Leukocyte differentiation antigen 74; CIITA: Class II transactivator; TAP: Transporters associated with antigen processing; ISGS: Interferon-stimulated genes; STAT1: Signal transducer and activator of transcription 1; ISG20: Interferon-stimulated gene 20; IKBKE: Inhibitor of nuclear factor kappa-B kinase subunit epsilon; SAMHD1: Sterile alpha motif and HD domain-containing protein 1; HLA: Human leukocyte antigen; LC: Liver cirrhosis; HCC: Hepatocellular carcinoma; HBV: Hepatitis B virus.

Citation: Li S, Xi Y, Dong XY, Yuan WB, Tang JF, Zhou CF. Evaluating the scope of human leukocyte antigen polymorphisms influencing hepatitis B virus-related liver cancer and cirrhosis through multi-clustering analysis. World J Gastroenterol 2025; 31(7): 102632
URL: https://www.wjgnet.com/1007-9327/full/v31/i7/102632.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i7.102632