Preliminary study on the loss of heterozygosity at 17p13 in gastric and colorectal cancers

doi:10.3748/wjg.v3.i3.160

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Sep 15, 1997 (publication date) through Dec 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 15, 1997; 3(3): 160-162
Published online Sep 15, 1997. doi: 10.3748/wjg.v3.i3.160

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Figure 1 Loss of heterozygosity (LOH) at 17p13 in gastric carcinoma. N: Normal DNA; T: Tumor DNA. (A) LOH at the p53 locus. Genomic DNA was digested with ScaI. Sample 4 showed heterozygosity, and Sample 6 showed LOH. (B) LOH at YNZ22. Genomic DNA was digested with TaqI. Samples 3 and 7 showed heterozygosity. Samples 1 and 5 showed LOH. (C) LOH at YNZ22. Genomic DNA was digested with MsqI, LOH was detected in Samples 2 and 4.

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Figure 2 Loss of heterozygosity (LOH) at 17p13 in colorectal cancer. N: Normal DNA; T: Tumor DNA. (A) LOH at p53. Genomic DNA was digested with ScaI. LOH was detected in Sample 2. (B) LOH at YNZ22. Genomic DNA was digested with MspI. LOH was detected in Samples 2 and 4.

Citation: Wu GJ, Shan XN, Li MF, Shi SL, Zheng QP, Yu L, Zhao SY. Preliminary study on the loss of heterozygosity at 17p13 in gastric and colorectal cancers. World J Gastroenterol 1997; 3(3): 160-162
URL: https://www.wjgnet.com/1007-9327/full/v3/i3/160.htm
DOI: https://dx.doi.org/10.3748/wjg.v3.i3.160