Copyright
©The Author(s) 2023.
World J Gastroenterol. Apr 28, 2023; 29(16): 2380-2396
Published online Apr 28, 2023. doi: 10.3748/wjg.v29.i16.2380
Published online Apr 28, 2023. doi: 10.3748/wjg.v29.i16.2380
Figure 1 Wnt signaling pathway.
LRP5/6: LDL-receptor-related protein 5/6; Dvl: Dishevelled; APC: Adenomatosis polyposis coli; GSK-3β: Glycogen synthase kinase-3β; CK1: Casein kinase 1.
Figure 2 Notch signaling pathway.
Figure 3 Hippo signaling pathway.
MST: Mammalian sterile; LATS: Large tumor suppressor; YAP: Yes-associated protein; TAZ: Tafazzin.
Figure 4 The Wnt/β-catenin signaling pathway promotes intestinal stem cells proliferation and maintains intestinal epithelial homeostasis.
ISCs: Intestinal stem cells.
Figure 5 Interaction between the Wnt pathway and Notch pathway.
EGF: Epidermal growth factor; BMP: Bone morphogenetic protein.
- Citation: Zheng L, Duan SL. Molecular regulation mechanism of intestinal stem cells in mucosal injury and repair in ulcerative colitis. World J Gastroenterol 2023; 29(16): 2380-2396
- URL: https://www.wjgnet.com/1007-9327/full/v29/i16/2380.htm
- DOI: https://dx.doi.org/10.3748/wjg.v29.i16.2380