Copyright
©The Author(s) 2023.
World J Gastroenterol. Apr 7, 2023; 29(13): 1982-1993
Published online Apr 7, 2023. doi: 10.3748/wjg.v29.i13.1982
Published online Apr 7, 2023. doi: 10.3748/wjg.v29.i13.1982
Figure 1 Enzymatic regulation of fatty acid aerobic oxidation.
SCFA: Short-chain-fatty acids; CPT1: Carnitine palmitoyltransferase-1; CPT2: Carnitine palmitoyltransferase-2; LCFA: Long-chain fatty acids; VLDL: Very low density lipoprotein; ACSL: Long-chain acyl-CoA synthetase; TCA: Tricarboxylic acid; ACS: Acyl-CoA synthetase; ACC: Acetyl-CoA carboxylase; ETC: Electronic respiratory chain; FASN: Fatty acid synthase.
Figure 2 Mitochondrial depolarization activates the PINK1/Parkin pathway to mediate mitophagy.
NIX: Nip3-like protein X; BNIP3: Bcl-219 kDa interacting protein.
Figure 3 Mitochondrial depolarization activates the PINK1/Parkin pathway to mediate mitophagy.
FFA: Free fatty acid; ROS: Reactive oxygen species; TCA: Tricarboxylic acid; mtDNA: Mitochondrial DNA; ETC: Electronic respiratory chain.
- Citation: Wang D, Ji DC, Yu CY, Wu DN, Qi L. Research progress on the mitochondrial mechanism of age-related non-alcoholic fatty liver. World J Gastroenterol 2023; 29(13): 1982-1993
- URL: https://www.wjgnet.com/1007-9327/full/v29/i13/1982.htm
- DOI: https://dx.doi.org/10.3748/wjg.v29.i13.1982