Hepatocellular carcinoma, decompensation, and mortality based on hepatitis C treatment: A prospective cohort study

Figure 1 Patient flow diagram. DAA: Direct-acting antivirals; dLC: Decompensated liver cirrhosis; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma; HCV: Hepatitis C virus; IBT: Interferon-based treatment; HIV: Human immunodeficiency virus; LT: Liver transplantation.

Figure 2 Cumulative incidences of hepatocellular carcinoma, decompensation, and death/transplantation in entire cohort. A: Cumulative incidence of hepatocellular carcinoma in the untreated, interferon-based treatment (IBT), and direct-acting antivirals (DAA) groups; B: Cumulative incidence of decompensation in the untreated, IBT, and DAA groups; C: Cumulative incidence of death/transplantation in the untreated, IBT, and DAA groups. DAA: Direct-acting antivirals; HCC: Hepatocellular carcinoma; IBT: Interferon-based treatment.

Figure 3 Cumulative incidences of hepatocellular carcinoma, decompensation, and death/transplantation in the matched sustained virologic response cohort. A: Cumulative incidence of hepatocellular carcinoma in the interferon-based treatment-sustained virologic response (IBT-SVR) and direct-acting antivirals-sustained virologic response (DAA-SVR) groups; B: Cumulative incidence of decompensation in the IBT-SVR and DAA-SVR groups; C: Cumulative incidence of death/Liver transplantation in the IBT-SVR and DAA-SVR groups. DAA: Direct-acting antivirals; HCC: Hepatocellular carcinoma; IBT: Interferon-based treatment; SVR: Sustained virologic response.