Diagnosis of erythropoietic protoporphyria with severe liver injury: A case report

Figure 1 Clinical features. Physical examination after admission showed severe yellowing of skin and sclera, rough and irregular skin on the arm, face and perioral area, and lichenification in some areas.

Figure 2 Accessory examinations. A: Abdominal image of magnetic resonance imaging; B: Peripheral blood (×20); C: Hematoxylin and eosin (HE)-stained skin biopsy (×100); D: Periodic acid-Schiff-stained skin biopsy (×100); E: HE-stained liver biopsy under a light microscope; F: HE-stained liver biopsy under a polarized light microscope.

Figure 3 First generation sequencing.

Figure 4 The diagnostic flow chart.