Long-term outcomes of endoscopic resection for small (≤ 4.0 cm) gastric gastrointestinal stromal tumors originating from the muscularis propria layer

Figure 1 Endoscopic full-thickness resection for a gastrointestinal stromal tumors located in the gastric fundus. A: Endoscopy showed a SET was located in the gastric fundus; B: EUS showed the same tumor mainly bulged into the extraluminal space and had an extensive connection to the MP layer of the stomach; C: The tumor, including its underlying MP and serosa, was resected; D and E: The gastric wall defect was closed using clips combined with an endoloop; F: The resection specimen was a 2.7 cm tumor; G: Immunohistochemistry showed that CD117 was present in most tumor cells (original magnification × 100); H: Mitotic figures could be found easily (original magnification × 400). EUS: Endoscopic ultrasonography.

Figure 2 Submucosal tunneling endoscopic resection for a gastrointestinal stromal tumors located in the gastric cardia. A: Endoscopy showed a SET was located in the gastric cardia; B: EUS showed the same tumor mainly bulged into the extraluminal space and had an extensive connection to the MP layer of the stomach; C: The tumor was resected from the MP layer via submucosal tunneling; D and E: The mucosal incision site was closed with several clips after tumor removal; F: The resection specimen was a 2.4 cm tumor; G: Immunohistochemistry showed that CD34 was present in most tumor cells (original magnification × 100); H: Mitotic figures could not be found (original magnification × 400). EUS: Endoscopic ultrasonography.