Early gastric cancer frequently has high expression of KK-LC-1, a cancer-testis antigen

Figure 1 Expression of Kita-Kyushu lung cancer antigen-1 in the gastric cancer tumors. The expression of KK-LC-1 was detected as a 342-bp band of the amplicon. The three specimens were assessed as KK-LC-1 positive (+) in this panel. The brightest band of top in lane M indicates 500 bp of 75 ng. M: 100 bp ladder; C: Negative control; –: KK-LC-1 negative; +: KK-LC-1 positive. KK-LC-1: Kita-Kyushu lung cancer antigen-1.

Figure 2 Ratio of CTA expression between early and advanced stage gastric cancer. These figures show a comparison of expression rates of each CTA between early and advanced stage. A: Distribution of expression rate of each CTA in early and advanced stages; B: Early/advanced stage expression ratios (E/A ratios) were used to evaluate whether the CTAs concerned were frequently expressed in early- as well as advanced-stage samples. (E/A ratio = expression rate of early stage/expression rate of advanced stage).