Copyright
©The Author(s) 2015.
World J Gastroenterol. Sep 21, 2015; 21(35): 10126-10136
Published online Sep 21, 2015. doi: 10.3748/wjg.v21.i35.10126
Published online Sep 21, 2015. doi: 10.3748/wjg.v21.i35.10126
Figure 1 High performance liquid chromatography of QHF group formula.
Figure 2 Changes in mouse body weight before and after drug administration.
Data are expressed as mean ± SD, n = 10. aP < 0.05, bP < 0.01 vs Model group; Control: Normal control group; Model: Model control group; DDP: Cisplatin group; QHF: QHF group; QHF + DDP: QHF plus cisplatin group.
Figure 3 Mouse liver tumor morphology.
Hematoxylin and eosin staining, magnification × 200. Control: Normal control group; Model: Model control group; DDP: Cisplatin group; QHF: QHF group; QHF + DDP: QHF plus cisplatin group.
Figure 4 Expression of hepatocyte growth factor in mouse liver tumor.
bP < 0.01 vs group C; dP < 0.01 vs group M. Control: Normal control group; Model: Model control group; DDP: Cisplatin group; QHF: QHF group; QHF + DDP: QHF plus cisplatin group.
Figure 5 c-Met protein expression and p-c-Met levels in mouse liver tumor.
bP < 0.01 vs group C; dP < 0.01 vs group M. Control: Normal control group; Model: Model control group; DDP: Cisplatin group; QHF: QHF group; QHF + DDP: QHF plus cisplatin group.
Figure 6 p38 protein expression and p-p38 levels in mouse liver tumor.
bP < 0.01 vs group C; dP < 0.01 vs group M. Control: Normal control group; Model: Model control group; DDP: Cisplatin group; QHF: QHF group; QHF + DDP: QHF plus cisplatin group.
Figure 7 ERK expression and p-ERK levels in mouse liver tumor.
bP < 0.01 vs group C; cP < 0.05, dP < 0.01 vs group M. Control: Normal control group; Model: Model control group; DDP: Cisplatin group; QHF: QHF group; QHF + DDP: QHF plus cisplatin group.
Figure 8 Vascular endothelial growth factor (VEGF) expression in mouse liver tumor.
aP < 0.05, bP < 0.01 vs group C; cP < 0.05, dP < 0.01 vs group M. Control: Normal control group; Model: Model control group; DDP: Cisplatin group; QHF: QHF group; QHF + DDP: QHF plus cisplatin group.
- Citation: Chen T, Yuan SJ, Wang J, Hu W. Mechanism of QHF-cisplatin against hepatocellular carcinoma in a mouse model. World J Gastroenterol 2015; 21(35): 10126-10136
- URL: https://www.wjgnet.com/1007-9327/full/v21/i35/10126.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i35.10126