Basic Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jun 7, 2015; 21(21): 6550-6560
Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6550
Figure 1
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Figure 1 Expression levels of VEGFA mRNA assessed by quantitative reverse transcription-polymerase chain reaction. A: Colorectal cancer (CRC) tissues and normal intestinal mucosa tissues; B: Tissues inside and outside the serosal layer; C: Tissues with and without lymph node metastasis (LNM); D: Tissues of tumor-node-metastasis (TNM) stages. aP < 0.05 vs control.
Figure 2
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Figure 2 Expression levels of APP mRNA assessed by quantitative reverse transcription-polymerase chain reaction. A: Colorectal cancer (CRC) tissues and normal intestinal mucosa tissues; B: Tissues inside and outside the serosal layer; C: Tissues with and without lymph node metastasis (LNM); D: Tissues of tumor-node-metastasis (TNM) stages. bP < 0.01 vs control.
Figure 3
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Figure 3 Expression levels of NUMB mRNA assessed by quantitative reverse transcription-polymerase chain reaction. A: Colorectal cancer (CRC) tissues and normal intestinal mucosa tissues; B: Tissues inside and outside the serosal layer; C: Tissues with and without lymph node metastasis (LNM); D: Tissues of tumor-node-metastasis (TNM) stages. bP < 0.01 vs control.
Figure 4
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Figure 4 Electrophoregram of alternative splicing variants in VEGFA, APP and NUMB. CRC: Colorectal cancer.
Figure 5
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Figure 5 Expression levels of alternative splice variants using polymerase chain reaction-restriction fragment length polymorphism analysis. Expression levels of A: VEGFA; B: APP; and C: NUMB alternative splice variants in colorectal cancer (CRC) tissues and normal intestinal mucosa tissues. aP < 0.05 and bP < 0.01 vs the control group.
Figure 6
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Figure 6 Expression levels of VEGFA165b assessed by quantitative reverse transcription-polymerase chain reaction. Expression levels of VEGFA165b in A: Colorectal cancer (CRC) tissues and normal intestinal mucosa tissues; B: Tissues inside and outside the serosal layer; C: Tissues with and without lymph node metastasis (LNM); and D: Tissues of tumor-node-metastasis (TNM) stages. bP < 0.01 vs control.