Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor

Figure 1 Esophagogastroduodenoscopy at admission. A huge bulging mucosa with an intact surface causing luminal narrowing at 35 cm from the incisor teeth was seen.

Figure 2 Endoscopic ultrasonography at admission. Irregular margined inhomogeneous hypoechoic lesion measuring approximately 35 mm × 22 mm in size with an obscure layer of origin was noted.

Figure 3 Abdominal computed tomography scan at admission. A well-defined mass measuring 35 mm in size in the distal esophagus was noted (arrow).

Figure 4 Histologic examination. Malignant gastrointestinal neuroectodermal tumor consisting of spindle cells with eosinophilic and clear cytoplasm and vesicular nuclei was noted. (HE stain, × 200).

Figure 5 Histologic examination with immunohistochemical staining. Positivity for S-100 (A) and SOX10 (B) was noted (× 200).