Mitochondrial uncoupling protein 2 and pancreatic cancer: A new potential target therapy

doi:10.3748/wjg.v21.i11.3232

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 21, 2015; 21(11): 3232-3238
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3232

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Figure 1 Uncoupling protein 2 uncoupling activity in oxidative phosphorylation. ROS: Reactive oxygen species; UCP2: Uncoupling protein 2; SOD: Superoxide dismutase; Mn-SOD: Manganese-superoxide dismutase.

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Figure 2 The regulation of cancer metabolism by uncoupling protein 2. ROS: Reactive oxygen species; UCP2: Uncoupling protein 2.

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Figure 3 Relation between cancer development and uncoupling protein 2 expression or activity. ROS: Reactive oxygen species; UCP2: Uncoupling protein 2.

Citation: Donadelli M, Dando I, Dalla Pozza E, Palmieri M. Mitochondrial uncoupling protein 2 and pancreatic cancer: A new potential target therapy. World J Gastroenterol 2015; 21(11): 3232-3238
URL: https://www.wjgnet.com/1007-9327/full/v21/i11/3232.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i11.3232