Intestinal ischemia-reperfusion of macaques triggers a strong innate immune response

Figure 1 Histological sections of ileum from the two groups (HE staining, × 400).

Figure 2 Expression of Toll-like receptor 4, Toll-like receptor 2, MD2, nuclear factor-κB and interferon-γ in the ileal epithelium and Peyer’s nodules of macaques (immunohistochemical stain, epithelium × 400, Peyer’s nodules × 200). TLR: Toll-like receptor; NF-κB: Nuclear factor-κB; IFN-γ: interferon-γ.

Figure 3 Expression of Toll-like receptor 4, Toll-like receptor 2, MD2, nuclear factor-κB and interferon-γ in the ileal epithelia of macaques. ^aP < 0.05 vs control group. TLR: Toll-like receptor; NF-κB: Nuclear factor-κB; IFN-γ: interferon-γ.

Figure 4 mRNA for Toll-like receptor 4, Toll-like receptor 2, MD2, TNF-α and IL-1β in ileal epithelia of macaques (RT-PCR). ^aP < 0.05 vs control group. TLR: Toll-like receptor; TNF-α: Tumor necrosis factor-α; IL-β: Interleukin-β; IIR: Intestinal ischemia-reperfusion; RT-PCR: Reverse transcription polymerase chain reaction.