Complex interactions between microRNAs and hepatitis B/C viruses

Figure 1 Summary of cellular miRNAs effect on hepatitis B virus and hepatitis C virus replication. A: The miRNAs which regulate hepatitis B virus (HBV) replication through targeting transcription factors known for HBV transcription, regulating immune, and direct targeting viral transcripts were indicated; B: The miRNAs which regulate hepatitis C virus (HCV) replication through targeting entry, translation, replication, envelopment, and regulating immune were indicated.

Figure 2 Summary of miRNAs and their targets associated hepatocellular carcinoma after hepatitis B virus or hepatitis C virus infection. miRNAs which are up-regulated in hepatocellular carcinoma (HCC) are indicated in red and miRNAs which are down-regulated in hepatocellular carcinoma are indicated in green. Data presented in this figure is based on literature and non-exhaustive. HBV/HCV: Hepatitis B virus or hepatitis C virus.