Chromoendoscopy of gastric adenoma using an acetic acid indigocarmine mixture

Figure 1 A case of tubular adenoma (no change in acetic acid indigocarmine mixture-chromoendoscopy). A: Whitish superficial elevated lesion is shown at the greater curvature of the antrum in white light endoscopy (indicated by yellow arrows); B: After sprinkling indigo carmine solution; C: 3 min after sprinkling acetic acid indigocarmine mixture (AIM) solution. Compared to B, there was no surface color change (no change in AIM-chromoendoscopy); D: Histology after endoscopic submucosal dissection.

Figure 2 A case of well-differentiated adenocarcinoma (reddish color change in acetic acid indigocarmine mixture-chromoendoscop). A: A normochromic superficial elevated lesion is shown at the lesser curvature of the antrum in white light endoscopy (indicated by yellow arrows); B: After sprinkling indigo carmine solution. The margin of the lesion was not clear; C: 3 min after sprinkling acetic acid indigocarmine mixture (AIM) solution. The margin of the lesion became clear and the surface color turned reddish (reddish change in AIM-chromoendoscopy); D: Histology after endoscopic submucosal dissection.