Coexistence of gastrointestinal stromal tumor, esophageal and gastric cardia carcinomas

Figure 1 Esophagography showed a filling defect in the anterior wall of the lower esophagus.

Figure 2 Computed tomography scan. A: Circumferential thickening (arrow) of the lower esophageal wall with loss of lumen; B: Lower level displayed focal thickening (arrow) of the gastric wall with marked enhancement; C and D: Lower levels displayed a large, heterogeneous, round mass close to the greater curvature of the stomach (arrows).

Figure 3 Microscopic images. A: Esophageal squamous cell carcinoma (×10); B: Gastric cardia adenocarcinoma (×10); C: Gastric gastrointestinal stromal tumor (×10); D-F: Immunohistochemistry indicated strong staining for Dog-1 (D, × 40), c-Kit/CD117 (E, ×10), Ki-67 (F, ×10).