Response evaluation of chemotherapy in metastatic colorectal cancer by contrast enhanced ultrasound

Figure 1 Contrast enhanced ultrasound. A: A representative liver metastasis after 13 s of contrast agent injection with early contrast enhancement; B: A representative liver metastasis after 29 s of contrast agent injection with lost of contrast enhancement.

Figure 2 Curves of contrast behavior in a liver metastasis (solid line, 1) and normal liver tissue (dotted line, 2) over the time (s = seconds) and percent of contrast enhancement (Si %).

Figure 3 Time to peak parameters. A: Time to peak (TTP) values measured in the metastasis between responders and non-responders on contrast enhanced ultrasound (CEUS) date 1, date 2 and date 3 (responders with complete response (CR), partial response (PR) and stable disease (SD) (n = 21) vs non-responder with progressive disease (PD) (n = 9); B:The TTP quotient between responders and non-responders on CEUS date 1, date 2 and date 3 (CR and PR were classified as responders (n = 13) and patients with SD and PD as non-responders (n = 17).