Clinicopathologic significance of GLUT1 expression and its correlation with Apaf-1 in colorectal adenocarcinomas

Figure 1 Representative photomicrograph of glucose transporter 1 immunostaining in normal mucosa (A), tubular adenoma with low grade dysplasia (B), tubular adenoma with high grade dysplasia (C), and adenocarcinoma (D). The glucose transporter 1 was stained in the cytoplasmic membrane of the cells.

Figure 2 Representation showing the difference of mean grading score of glucose transporter 1 expression in normal mucosa, tubular adenomas with low grade dysplasia, tubular adenomas with high grade dysplasia, adenocarcinomas, and metastatic lesions (lymph nodes and distant organs). One-way ANOVA test was used. GLUT1: Glucose transporter 1; LGD: Low grade dysplasia; HGD: High grade dysplasia.

Figure 3 Cumulative overall survival curves (A) and disease-free survival curves (B) according to glucose transporter 1 expression in 515 colorectal cancer patients (Kaplan-Meier method with log-rank test). GLUT1: Glucose transporter 1.