Eight-year survival after advanced gastric cancer treated with S-1 followed by surgery

Figure 1 Abdominal computed tomography (CT). A: Marked swelling of paraaortic lymph nodes before treatment (arrow); B: After two courses of S-1, abdominal CT showed remarkable reductions (arrow).

Figure 2 CT shows a Virchow’s (A) and an axillary lymph node (B) which were reduced remarkably in size after treatment.

Figure 3 Resected specimen shows a concave lesion of 45 mm × 40 mm (arrows) with an ulceration scar which was located in the lesser curvature in the middle of the stomach.

Figure 4 Histopathological examination. A: Histopathological examination showed numerous poorly differentiated adenocarcinoma cells in the mucosa; B: There were only a small number of poorly differentiated adenocarcinoma cells, but severe fibrosis, in the submucosal layer; C: The only findings in the lymph nodes were remarkable fibrosis and giant cells, with no cancer cells seen.