Ischemic preconditioning-induced hyperperfusion correlates with hepatoprotection after liver resection

Figure 1 Changes in portal vein (PV) and hepatic artery (HA) inflow (100% = baseline) at operation (mean ± SD) in the control group (A) and study population (B). T1: Before starting the Pringle maneuver; T2: At the end of the IP procedure, i.e. 10 min ischemia and 10 min of reperfusion; T3: One minute of simultaneous reperfusion of PV and HA; T4: Immediately before abdominal closure (29 ± 6 min and 32 ± 4 min after stopping portal triad crossclamping in group A and B, respectively). ^aP < 0.05, ^bP < 0.01 vs baseline.

Figure 2 The Pearson product moment correlation between HA flow and alanine aminotransferase (ALT) levels. On day 1, there is an inverse correlation (P < 0.05) in the control group (A) undergoing PM (r = -0.62). In patients undergoing IP prior to PM (B), an even stronger correlation (r = -0.73, P < 0.01) was found. Straight lines represent regression analysis; data include values of all patients.