Protective effects of electroacupuncture on acetylsalicylic acid-induced acute gastritis in rats

Figure 1 Protective effect of pretreatment of EA on ASA-induced gastric lesions in rats. Data are presented as the mean ± SE (n = 8 each group). ^aP < 0.05 compared with ASA group. ASA: Acetylsalicylic acid (100 mg/kg); EA: Electro-acupuncture.

Figure 2 Determination of gastric acidity was measured in terms of each group. Rats were treated with or without 100 mg/kg ASA after anesthesia and pretreatment of EA on ST-36 for 30 min. Data are presented as the mean ± SE. ^aP < 0.05 compared with Control group. Control: Distilled water (n = 5); ASA: Acetylsalicylic acid (100 mg/kg, n = 7); and EA+ASA: Electro-acupuncture on ST-36 + ASA (n = 8).

Figure 3 Expression of COX-1, 2 mRNAs in the rat stomach after oral administration of DW, ASA (100 mg/kg) or ASA (10 mg/kg) with EA pretreatment (n = 3 each group). A: Control; B: one hour after administration of ASA (100 mg/kg); C: Two hours after administration of ASA (100 mg/kg); D: Four hours after administration of ASA (100 mg/kg); E: One hour after administration of ASA (100 mg/kg) with EA pretreatment; F: Two hours after administration of ASA (100 mg/kg) with EA pretreatment; G: Four hours after administration of ASA (100 mg/kg) with EA pretreatment. ASA: Acetylsalicylic acid; EA: Electroacupuncture.

Figure 4 Total nitric oxide (NO) concentration of each group. Values are each a mean ± SE (n = 5 each group). ^aP < 0.05 compared with Control; ^cP < 0.05 compared with ASA group. Control: Distilled water, ASA: Acetylsalicylic acid (100 mg/kg); EA: Electro-acupuncture.