Gene expression and MR diffusion-weighted imaging after chemoembolization in rabbit liver VX-2 tumor model

Figure 1 A-D represent VX-2 tumor center, VX-2 tumor periphery, VX-2 tumor outer layer and normal liver parenchyma around tumor respectively. The ADC levels and signal were measured on DWI, and the samples were investigated by histopathology.

Figure 2 Positive gene expression in VX-2 tumor. A: PCNA; B: Bax; C: nm23; D: E-cad.

Figure 3 Image manifestations of hepatic VX-2 tumor on DWI and ADC map when b-value was 100 s/mm², 6 h after chemoembolization. A: High signal and distinct margins of VX-2 tumor on DWI; B: Low signal on the ADC map.

Figure 4 High uneven signal and distinct margins of hepatic VX-2 tumor on DWI and ADC map when b-value was 100 s/mm², 32 h after chemoembolization. A: High and uneven signal and distinct margins on DWI; B: Low or equal signal on ADC map.