Changes in count and function of splenic lymphocytes from patients with portal hypertension

Figure 1 CD20 immunostaining for distribution of B lymphocytes. There was no significant difference in distribution of B lymphocytes between PH and control groups; they were all mainly located in the splenic corpuscle. A: Control group; B: PH group (× 100).

Figure 2 CD3 immunostaining for distribution of T lymphocytes. There was no significant difference in distribution of T lymphocytes between PH and control groups; they were all mainly located in the marginal zone and PALS. A1: Control group, marginal zone; A2: Control group, PALS; B1: PH group, marginal zone; B2: PH group, PALS (× 100).

Figure 3 CD20 immunostaining for density of B lymphocytes. Compared to the control group, the density of B lymphocytes in the PH group decreased significantly in the splenic corpuscle and RP. A1: Control group, splenic corpuscle; A2: Control group, RP; B1: PH group, splenic corpuscle; B2: PH group, RP (× 100).

Figure 4 CD3 immunostaining for density of B lymphocytes. Compare to the control group, the density of T lymphocytes in the PH group decreased significantly in PALS. A: Control group; B: PH group (× 100).