Computer-aided morphometry of liver inflammation in needle biopsies

Math 1 Math(A1).

Figure 1 Liver biopsy section immunohistochemically treated with antibodies against LCA (A) and computer-aided recognition of the inflammatory cell network (B).

Figure 2 Border of clustered and non-clustered inflammatory cells.

Figure 3 Geometrical structure of clustered inflammatory cells. A_B=true area of the biopsy sample; A_C=area of the triangulation-defined cluster (necrosis attraction zone); A_CINF=sum of the areas of cluster-resident inflammatory cells; A_PINF=dispersed non-clustered cells.

Figure 4 High percentage of macrophages among dispersed cells (A) and low percentage in clusters of lymphocytes and other inflammatory cells (B).