Changes of the intestinal endocrine cells in the C57BL/6 mouse after implantation of murine lung carcinoma (3LL): An immunohistochemical quantitative study

Figure 2 Serotonin-IR cells of the duodenum (A, G), jejunum (B, H), ileum (C, I), cecum (D, J), colon (E, K) and rectum (F, L) of non-implanted Sham (A-F) and 3LL-implanted group (G-L). In 3LL-implanted group, serotonin-IR cells were dramatically decreased in the entire intestinal regions. A, B, D-L: ×120; C: ×240; PAP methods.

Figure 3 Somatostatin-IR cells of the duodenum (A, D), jejunum (B, E) and ileum (C, F) of non-implanted Sham (A-C) and 3LL-implanted group (D-E). In 3LL-implanted group, somatostatin-IR cells were slightly decreased in the jejunum and ileum. A, C-F: ×240; B: ×120; PAP methods.

Figure 1 CGA-IR cells of the duodenum (A, G), jejunum (B, H), ileum (C, I), cecum (D, J), colon (E, K, L) and rectum (F, M) of non-implanted Sham (A-F) and 3LL-implanted group (G-M). In 3LL-implanted group, CGA-IR cells were dramatically decreased in the entire intestinal regions. A-C, E, G, H and K: ×120; D, F, I, J and L: ×240; M: ×480; PAP methods.

Figure 4 Glucagon-IR cells were restricted to the ileum (A) and colon (B) of non-implanted Sham. They were located in the intestinal gland regions. A: ×240; B: ×480; PAP methods.

Figure 5 CCK-8-IR cells of the duodenum (A, C) and jejunum (B, D) of non-implanted Sham (A, B) and 3LL-implanted group (C, D). In 3LL-implanted group, CCK-8-IR cells were decreased in the jejunum. A, C: ×120; B, D: ×240; PAP methods.