MUC1 and MUC5AC mucin expression in liver fluke-associated intrahepatic cholangiocarcinoma

Figure 1 Staining patterns of MUC1 and MUC5AC core proteins. A and C: Immunohistochemical staining of MUC1 and MUC5AC apomucins expressed in tumor tissues, respectively. B and D: MUC1 and MUC5AC staining of vascular and neural-invaded tumor cells.

Figure 2 Survival curves using Kaplan-Meier method. A: Significant unfavorable prognosis of tumors with high expression of MUC1 compared to low-expression carcinoma (P = 0.0002); B: Poor survival of patients with tumors having a high expression of MUC5AC as opposed to patients having a low-expression carcinoma.