HMLH1 gene mutation in gastric cancer patients and their kindred

Figure 1 SSCP analysis of the normal and mutant samples of hMLH1 gene exon 8 (A) and exon 12 (B). Peaks 3, 4, 6- wild type ssDNA and peaks 1, 2, 5-mutant ssDNA for exon 8 (A); Peaks 1, 4-wild type ssDNA, peaks 2, 3-mutant ssDNA and peaks 5, 6-primer ssDNA for exon 12 (B).

Figure 2 Electrophorogram section of CE-sequencing of hMLH1 gene exon 8 (A) and exon 12 (B). Arrow: substitution of A-G (A) and T-A (B).