Disseminated tumor cells homing into rats’ liver: A new possible mechanism of HCC recurrence

Figure 1 The blue blots under the purple background indicated Y chromosomes in these nuclei of recurrent tumor cells with 10 × 10 magnification microscope. The capsule definitely parted the recurrent tumor tissue from the recipient liver parenchyma. No positive signals were found out in the para-tumor tissue.

Figure 2 It is acknowledged that there exist two HCC recur-ring mechanisms of intrahepatic metastasis through portal venous system and multicentric occurrence from cirrhotic nodules. These extrahepatic cells homing into liver may be a new mechanism after liver transplantation. Likewise, it impli-cates that this mechanism is responsible for HCC recurrence after hepatectomy.