Effect of local CTLA4Ig gene transfection on acute rejection of small bowel allografts in rats

Figure 1 Heterotopic small bowel transplantation in the rat. The vasculature of the graft has been anastomosed. RSB: recipient’s small bowel. TSB: transplanted small bowel.

Figure 2 Presence of CTLA4Ig in the small bowel allografts. CTLA4Ig was stained as the brown granules. A, B, C represent the cryostat sections of CTLA4Ig gene transfected grafts on d 3, 7, 10 after transplantation, respectively. D represent the cryostat sections of non-CTLA4Ig gene transfected grafts, expression of CTLA4Ig was not detected. [original magnification ×200].

Figure 3 Apoptotic crypt cells in the small bowel allografts. A1, B1, C1 represent the tissue sections of non-CTLA4Ig gene transfected grafts obtained on d 3, 7, 10 after transplantation, respectively. A2, B2, C2 represent the tissue sections of CTLA4Ig gene transfected grafts obtained on d 3, 7, 10 after transplantation, respectively. [original magnification ×400].