Preparation and characteristics of DNA-nanoparticles targeting to hepatocarcinoma cells

Figure 1 Transmission electron microphotography of TK-PLGA nanoparticles.

Figure 2 Agarose gel electrophoresis of DNA extracted from nanoparticles after treatment with sonication and Dnase I. Lane 1 represented untreated control plasmid DNA, lane 2 repre-sented plasmid DNA incubated with Dnase I at 37 °C for 1 h, and lane 3, 4, 5, 6 indicated DNA extracted from PLGA nanoparticles incubated with Dnase I at 37 °C for 0, 4, 8, or 16 h, respectively.