Systematic Reviews
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 14, 2025; 31(6): 97697
Published online Feb 14, 2025. doi: 10.3748/wjg.v31.i6.97697
Prognostic roles nutritional index in patients with resectable and advanced biliary tract cancers
Di Zeng, Ning-Yuan Wen, Yao-Qun Wang, Nan-Sheng Cheng, Bei Li
Di Zeng, Ning-Yuan Wen, Yao-Qun Wang, Nan-Sheng Cheng, Bei Li, Division of Biliary Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Di Zeng, Ning-Yuan Wen, Yao-Qun Wang, Nan-Sheng Cheng, Bei Li, Research Center for Biliary Diseases, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Zeng D conceptualized and designed the research; curated and analyzed the data; developed the methodology; conducted investigations; prepared the original draft; and led the review and editing of the manuscript; Wen NY contributed to the conceptualization, formal analysis, and investigation, as well as the critical review and editing of the manuscript; Wang YQ was involved in investigations and contributed to the critical review and editing of the manuscript; Li B provided essential methodological support, supervised the project, and contributed to the manuscript review; Cheng NS secured funding for the research, supervised the entire project, and contributed to the manuscript review. Both Li B and Cheng NS have made critical and indispensable contributions as co-corresponding authors. Li B provided vital support in methodological design, supervised the research process, and ensured the scientific rigor of the manuscript. Cheng NS played a pivotal role in overseeing the project's progression, securing funding, interpreting results, and revising the manuscript. Their collaboration was instrumental in shaping the manuscript and bringing it to publication.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nan-Sheng Cheng, PhD, Division of Biliary Surgery, Department of General Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan Province, China. nanshengcheng@yeah.net
Received: June 5, 2024
Revised: October 24, 2024
Accepted: December 16, 2024
Published online: February 14, 2025
Processing time: 218 Days and 20.9 Hours
Core Tip

Core Tip: Preoperative prognostic nutritional index (PNI) serves as a valuable prognostic tool for patients with biliary tract cancer (BTC). Our meta-analysis, comprising 17 studies and 4645 patients, reveals that low preoperative PNI significantly correlates with poorer overall survival and disease-free survival in BTC patients, irrespective of subtype or stage. These findings underscore the importance of incorporating PNI assessment into preoperative evaluations for effective risk stratification and personalized treatment strategies in BTC. Further prospective studies are warranted to validate these results and optimize patient management approaches.