Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 7, 2025; 31(5): 101280
Published online Feb 7, 2025. doi: 10.3748/wjg.v31.i5.101280
Clinicopathological features and treatment of gastrointestinal schwannomas
Peng-Cheng Zhang, Shu-Hui Wang, Jun Li, Jing-Jie Wang, Hong-Tan Chen, Ai-Qing Li
Peng-Cheng Zhang, Jing-Jie Wang, Hong-Tan Chen, Ai-Qing Li, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China
Shu-Hui Wang, Department of Epidemiology & Health Statistics, School of Public Health, School of Medicine, Zhejiang University, Hangzhou 310058, Zhejiang Province, China
Jun Li, Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China
Co-first authors: Peng-Cheng Zhang and Shu-Hui Wang.
Author contributions: Zhang PC and Wang SH contributed equally to this work; Li AQ designed the study and was responsible for developing the methodology and the accuracy of the data analysis; Li AQ, Zhang PC, and Wang SH participated in the formal analysis and investigation; Li J reviewed all histological samples to confirm the diagnosis; Li AQ, Zhang PC, and Wang SH performed data analysis and wrote the original draft; Li AQ, Zhang PC, Wang SH, Li J, Wang JJ, and Chen HT participated in the review and editing; All authors have read and approved the final manuscript.
Institutional review board statement: This study was conducted in strict accordance with the ethical guidelines outlined in the Declaration of Helsinki and received approval from the Clinical Research Ethics Committee of the First Affiliated Hospital, Zhejiang University, School of Medicine, No. 2024-0589.
Informed consent statement: Written informed consent was waived considering the retrospective study design.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets analyzed in the current study are available from the corresponding author on reasonable request. Please email the corresponding author at 3310015@zju.edu.cn.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ai-Qing Li, MD, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qinchun Road, Hangzhou 310003, Zhejiang Province, China. 3310015@zju.edu.cn
Received: September 9, 2024
Revised: November 11, 2024
Accepted: December 13, 2024
Published online: February 7, 2025
Processing time: 111 Days and 15.7 Hours
Core Tip

Core Tip: Gastrointestinal schwannomas (GIS) are rare neurogenic tumors of the gastrointestinal tract, posing considerable challenges in diagnosis and treatment. We retrospectively analyzed the clinical features, pathological characteristics, treatment outcomes, associated comorbidities, and prognosis of 229 patients diagnosed with GIS between June 2007 and April 2024. Our findings emphasize the critical role of endoscopy in improving diagnostic accuracy, guiding treatment strategies, and enhancing patient outcomes.