Rectal neuroendocrine tumors: Can we predict their behavior?

doi:10.3748/wjg.v31.i5.101150

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Feb 7, 2025 (publication date) through Jan 29, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 7, 2025; 31(5): 101150
Published online Feb 7, 2025. doi: 10.3748/wjg.v31.i5.101150

Rectal neuroendocrine tumors: Can we predict their behavior?

Elisabetta Dell'Unto, Francesco Panzuto, Gianluca Esposito

Elisabetta Dell'Unto, Francesco Panzuto, Gianluca Esposito, Department of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome 00189, Lazio, Italy

Author contributions: Dell’Unto E performed the research and drafted the manuscript; Panzuto F and Esposito G interpreted the data and critically reviewed the manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Gianluca Esposito, MD, PhD, Senior Researcher, Department of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Via G Papanicolau Snc, Rome 00189, Lazio, Italy. gianluca.esposito@uniroma1.it

Received: September 5, 2024
Revised: November 23, 2024
Accepted: December 3, 2024
Published online: February 7, 2025
Processing time: 116 Days and 1.1 Hours

Core Tip

Core Tip: This study proposes the GATIS score, an innovative model designed to predict individualized survival outcomes in patients with rectal neuroendocrine tumors. This model analyzes the relationship between clinicopathological features and patient prognoses. Nevertheless, additional prognostic factors (such as genetic and molecular markers) need to be investigated with further larger multicentric prospective studies.