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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 28, 2025; 31(4): 100718
Published online Jan 28, 2025. doi: 10.3748/wjg.v31.i4.100718
Published online Jan 28, 2025. doi: 10.3748/wjg.v31.i4.100718
Advances in gastrointestinal vascular bleeding disorders: Successful sirolimus treatment in colonic angioectasia
Qi Sun, Xiao-Ying Wang, Dong-Hao Li, Bai-Rong Li, Zhi-Meng Jiang, Shou-Bin Ning, Tao Sun, Department of Gastroenterology, Air Force Medical Center, Beijing 100142, China
Xiao-Ying Wang, College of Life Science, Northwest University, Xi’an 710069, Shaanxi Province, China
Xin-Zhuo Tu, Department of Pathology, Air Force Medical Center, Beijing 100142, China
Co-first authors: Qi Sun and Xiao-Ying Wang.
Co-corresponding authors: Shou-Bin Ning and Tao Sun.
Author contributions: Sun Q and Wang XY designed the study, acquired and analyzed data and wrote the manuscript; Li DH and Li BR collected the data; Tu XZ and Jiang ZM contributed analytic tools; Ning SB and Sun T provided supervision and guidance, reviewed and edited the manuscript and handled submission and communication; All authors have read and approved the final manuscript; Sun Q and Wang XY have both made significant and equal intellectual contributions to this study, as study design, data acquisition and analysis, manuscript writing, they worked together through multiple revisions and discussions to finalize the manuscript; As co-corresponding authors, Ning SB and Sun T made significant contributions in supervision and guidance, manuscript revision, submission and communication; We believe that this detailed contributions statement supports our designation of co-first authors and co-corresponding authors, accurately reflecting the contributions of each author to the study.
Supported by the Air Force Medical Center Youth Talent Program Project, No. 22YXQN034; Capital Health Development Research Special Project, No. 2020-4-5123; and Beijing Haidian District Health and Wellness Development Scientific Research Cultivation Program, No. HP2021-03-80803.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tao Sun, MD, PhD, Department of Gastroenterology, Air Force Medical Center, No. 30 Fucheng Road, Haidian District, Beijing 100142, China. suntao8703@126.com
Received: August 26, 2024
Revised: November 27, 2024
Accepted: December 9, 2024
Published online: January 28, 2025
Processing time: 127 Days and 22.8 Hours
Revised: November 27, 2024
Accepted: December 9, 2024
Published online: January 28, 2025
Processing time: 127 Days and 22.8 Hours
Core Tip
Core Tip: This study uncovers a pivotal shift from traditional endoscopic methods to pharmacological strategies in managing gastrointestinal vascular bleeding disorders. Notably, it highlights the novel use of sirolimus in effectively treating colonic angioectasia, offering fresh insights and potential improvements in patient outcomes.